Manchester City striker Sergio Aguero will miss the game against Cardiff on Wednesday night.
Manager Pep Guardiola broke the news at his press conference on Tuesday, but did not confirm the type of injury.
Aguero failed to train on Monday or Tuesday which forced Guardiola to not risk the Premier League’s top goal scorer.
The Argentine scored the second in City’s 2-0 victory over Fulham on Saturday, but hobbled off with an injury before the hour mark.
However, Guardiola is hopeful that his main talisman will be fit for Saturday’s FA Cup semi-final against Brighton.